The 1950 Western Reserve Red Cats football team represented the Western Reserve University—now known as Case Western Reserve University—as a member of the Mid-American Conference (MAC) during the 1950 college football season. Led by Richard W. Luther in his second and final season as head coach, the Red Cats compiled an overall record of 2–8 with a mark of 1–3 in conference play, tying for fourth place in the MAC. Lou Zontini served as an assistant coach for the team.